IDENTIFICATION OF PENEXANTHONE A AS A NOVEL CHEMOSENSITIZER TO INDUCE FERROPTOSIS BY TARGETING NRF2 IN HUMAN COLORECTAL CANCER CELLS

Identification of Penexanthone A as a Novel Chemosensitizer to Induce Ferroptosis by Targeting Nrf2 in Human Colorectal Cancer Cells

Ferroptosis has emerged as a potential mechanism for enhancing the efficacy of chemotherapy in cancer treatment.By suppressing nuclear factor erythroid 2-related factor 2 (Nrf2), cancer cells may lose their ability to Bag Cutters counteract the oxidative stress induced by chemotherapy, thereby becoming more susceptible to ferroptosis.In this study,

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